Renova®, Retin-A® and Avage® are vitamin A derivatives that have been used for years to treat teenage acne. It is only FDA-approved for that use. However, over the years, many doctors have found it to be effective in removing superficial skin lesions, sun-damaged areas, and removal of fine wrinkles. Like glycolic acid, Renova® and Retin-A® remove the dead-cell layer of the skin; but in addition, they stimulate epidermal turnover, which speeds regeneration of the skin. Over time, Renova® and Retin-A® may stimulate collagen production in the upper layers of the dermis.

Retin-A® can be irritating to the skin when first used. This is a medical condition called retinoid dermatitis." By starting out gradually and increasing concentration over time, this irritation can be greatly reduced, if not totally eliminated. The doctor will prescribe a concentration based on the individual's skin type. Renova® has the advantage of causing less irritation. Ironically, the Renova® is actually stronger than most concentrations of Retin-A®.

A pea-sized amount of Retin-A® or Renova® is placed in each of the four facial quadrants and then worked into the skin. This is usually done at bedtime. Initially, we recommend applying every other night and then gradually increasing to a daily application. If irritation develops, the dosage would be cut back to every other day or would be diluted with moisturizer. Because these Retin-A® derivatives remove the dead-cell layers of the skin, which can act as a filter, skin may burn more easily. For this reason, you may need to use sunscreen. If one if going to be out under intense sun, temporarily stopping use of the Retin-A® or Renova® may be advisable. Retin-A® and Renova® may also cause skin to become drier so moisturizers may need to be used as well.